P53

Recent important research results of tumor suppressor p53!

Recent important research results of tumor suppressor p53!

1.Cell Rep: Uncovering the new molecular mechanism of tumor suppressor p53-induced cancer cell death doi: 10.1016 / j.celrep.2020.03.011 There has been an ongoing battle between cancer cells and p53. P53 is […]

p53 target new drug! Aprea’s Blood Cancer Combination Therapy Receives FDA Breakthrough Therapy Designation

p53 target new drug! Aprea’s Blood Cancer Combination Therapy Receives FDA Breakthrough Therapy Designation

Aprea Therapeutics is a Boston-based biopharmaceutical company focused on developing and commercializing innovative cancer therapies that reactivate the tumor suppressor protein p53. Recently, the company announced that the U.S. food […]

Science Translational Medicine: Synthetic mRNA nanoparticle-mediated restoration of p53 tumor suppressor sensitizes p53-deficient cancers to mTOR inhibition

Science Translational Medicine: Synthetic mRNA nanoparticle-mediated restoration of p53 tumor suppressor sensitizes p53-deficient cancers to mTOR inhibition

In a new study, using advances in nanotechnology, researchers have found that restoring p53 not only delays the growth of p53-deficient liver and lung cancer cells, but may also make cancer drugs mTOR inhibitors […]

Cell Journal: the Anticancer Gene p53 can prevent birth defects.

Cell Journal: the Anticancer Gene p53 can prevent birth defects.

A recent study published in the journal Cell Reports reveals that the famous tumor suppressor gene p53 and the development of neural tubes in female embryos are surprisingly critical. The […]

Tumor suppressor gene p53 can promote tumor growth!

P53 is a well-known human anticancer protein, known as the guardian of the human genome. Wild-type p53 (WTp53) are widely found in nature. Recently, scientists from the University of California found […]

Star tumor suppressor gene p53

Introduction P53 tumor suppressor gene is a kind of gene that inhibits cells from transforming into cancer cells in living organisms. There are oncogene and tumor suppressor gene in the […]