A mass of studies have revealed that mTOR is a serine/threonine protein kinase closely related to the occurrence of A mass of studies have revealed that mTOR is a serine/threonine […]
In a new study, using advances in nanotechnology, researchers have found that restoring p53 not only delays the growth of p53-deficient liver and lung cancer cells, but may also make cancer drugs mTOR inhibitors […]
Rapamycin (RAPA), also known as “sirolimus”, was first discovered by scientists in the soil of Easter Island, Chile in 1975 due to its strong antifungal properties. Rapamycin is a macrolide […]
Although the role of autophagy in cancer is very complex, various pharmacological agents with different antineoplastic properties have been shown to induce autophagic activity resulting in massive death of cells […]
Ras has been described to promote proliferation, suppress apoptosis, alter cell metabolism, disrupt morphogenesis, promote evasion of the immune system, induce remodeling of the microenvironment and stimulate metastasis. These functions are […]