mRNA

mRNA-vaccine

Common Nucleosides as Raw Materials for In Vitro Diagnosis

Messenger RNA (mRNA) was first discovered in the 1960s, but its instability and immunogenicity have severely hindered the development of mRNA therapy. To solve this problem, researchers have contrived several […]

Science Translational Medicine: Synthetic mRNA nanoparticle-mediated restoration of p53 tumor suppressor sensitizes p53-deficient cancers to mTOR inhibition

Science Translational Medicine: Synthetic mRNA nanoparticle-mediated restoration of p53 tumor suppressor sensitizes p53-deficient cancers to mTOR inhibition

In a new study, using advances in nanotechnology, researchers have found that restoring p53 not only delays the growth of p53-deficient liver and lung cancer cells, but may also make cancer drugs mTOR inhibitors […]