Facing the Coronavirus with continuous mutations, researchers are working hard to develop effective and broad-spectrum anti-Coronavirus drugs and vaccines. At the end of 2021, the small molecule oral drug was […]
The Coronavirus outbreak has posed a great threat to human health. Facing the continuous mutation of Coronavirus, researchers are working hard to develop effective and broad-spectrum anti-COVID-19 drugs as well […]
Abnormally high expression of indoleamine 2, 3-dioxygenase 1 (IDO1) is closely related to tumor immune escape and is an important target of tumor immunotherapy. In-depth research on the structure and […]
A mass of studies have revealed that mTOR is a serine/threonine protein kinase closely related to the occurrence of A mass of studies have revealed that mTOR is a serine/threonine […]
As the basic substance of life, carbohydrate molecules participate in almost all aspects of life activities and play various important biological functions. Based on the extensive biological functions of carbohydrate, […]
Abstract Immunotherapy has become an indispensable part of cancer treatment. A pivotal phagocytosis checkpoint, named cluster of differentiation 47 (CD47), which functions as a ‘don’t eat me’ signal to protect […]
In the latest issue of the JMC journal, a review article, entitled “A Decade of FDA-Approved Drugs (2010-2019): Trends and Future Directions”, was published, which analyzed and summarized the FDA-approved […]
05 Cardiovascular system drugs The sodium-glucose cotransporter 2 (SGLT-2) inhibitor dapagliflozin (Andaton; AstraZeneca) has been on the market as a hypoglycemic agent for nearly 10 years. Another indication of the […]
The birth of penicillin in 1943 opened the golden age of antimicrobial therapy. However, after the 1980s, large pharmaceutical companies faced major scientific challenges in finding new antibiotics to solve […]
Exatecan Mesylate is a semi-synthetic water-soluble derivative of camptothecin. It is a new type of topoisomerase I inhibitor with anti-tumor activity. The anhydrous, alkali-free form of the drug is called […]
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