This drug reduces excessive inflammatory responses from patients receiving immunotherapy. Researchers initially used the drug called tocilizumab monoclonal antibody against tocilizumab to treat patients with the most severe symptoms especially those […]
Introduction of JAK-STAT signaling Pathway The JAK-STAT signaling pathway is a signal transduction pathway stimulated by cytokines, which is involved in many important biological processes such as cell proliferation, differentiation, […]
Inflammation Inflammation is a self-limiting, localized response to any tissue injury or trauma caused by wounding or infection, and is characterized by redness, heat, pain and swelling (rubor, calor, dolor, […]
Introduction Oxygen is life sustaining, but its metabolism by organisms is not without consequences. Aerobic metabolism provides energy predominantly through mitochondrial oxidative phosphorylation. This process leads to the formation of by-products known […]
Celastrol, a quinine methide triterpene extracted from the perennial vine Tripterygium wilfordii (Celastraceae), has been used in traditional Chinese medicine as a natural remedy for inflammation and a variety of […]