geldanamycin

drug

Research Progress of Small Molecule Inhibitors Targeting MYC

MYC protein is an inherently disordered protein, which lacks a hydrophobic pocket or groove suitable for binding small molecule compounds. Currently, no small molecule compounds that can bind MYC have […]

Recent Updates on the Development of Ganetespib as a Hsp90 Inhibitor

Recent Updates on the Development of Ganetespib as a Hsp90 Inhibitor

Heat shock protein 90 (Hsp90) is a highly conserved molecular chaperone which modulates cellular homeostasis and environmental stress responses by interacting with more than 200 proteins, also known as Hsp90 client proteins, […]