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In 2007, Japanese professors firstly discovered ALK rearrangement and identified the fusion of ALK and EML4 in non-small cell lung cancer specimens. EML4 can promote the activation of ALK kinase […]
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Pharmaceutical analysis and testing can study the composition, physical and chemical properties, authenticity, purity, and the content of active ingredients of drugs, which ensures that people can use drugs reasonably […]
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As the basic substance of life, carbohydrate molecules participate in almost all aspects of life activities and play various important biological functions. Based on the extensive biological functions of carbohydrate, […]
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The development of antibody-drug conjugates (ADCs) has progressed significantly over the past decade due to improvements in payloads, linkers, and conjugation methods. In particular, linker design plays a key role […]
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The development of antibody-drug conjugates (ADCs) has progressed significantly over the past decade due to improvements in payloads, linkers, and conjugation methods. In particular, linker design plays a key role […]
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Plitidepsin was originally obtained from a kind of protozoans, called Aplidiumalbicans. Plitidepsin, also known as dehydrodidemnin B, is a member of the class of compounds known as didemnins. Didemnins are […]
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A recent article published by the well-known medical and health information website Xconomy pointed out that many new drugs are expected to be approved to enter the market before the end of […]
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Benzimidazolium is a benzo heterocycle compound containing two nitrogen atoms. Benzimidazole has a special chemical structure which can form hydrogen bonds with enzymes and receptors in organisms, coordinate with metal […]
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Phosphate is an important part of nucleic acid, a large number of which exists in the human body, it is a kind of harmless endogenous substances, which can help drugs […]
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Oxygen heterocyclic ring is one of the most common heterocyclic rings in drugs and natural products. By the end of 2017, 311 drug molecules had at least one oxygen heterocyclic […]