drug

drug

A Brief Discussion on ALK Inhibitors

In 2007, Japanese professors firstly discovered ALK rearrangement and identified the fusion of ALK and EML4 in non-small cell lung cancer specimens. EML4 can promote the activation of ALK kinase […]

molecular

Common Methods of Drug Analysis

Pharmaceutical analysis and testing can study the composition, physical and chemical properties, authenticity, purity, and the content of active ingredients of drugs, which ensures that people can use drugs reasonably […]

drug

Approved Carbohydrate-based Drugs During 2000-2021

As the basic substance of life, carbohydrate molecules participate in almost all aspects of life activities and play various important biological functions. Based on the extensive biological functions of carbohydrate, […]

ADCs

Recent Advances in ADC Linker

The development of antibody-drug conjugates (ADCs) has progressed significantly over the past decade due to improvements in payloads, linkers, and conjugation methods. In particular, linker design plays a key role […]

ADC linker

Types of ADC Linkers

The development of antibody-drug conjugates (ADCs) has progressed significantly over the past decade due to improvements in payloads, linkers, and conjugation methods. In particular, linker design plays a key role […]

What is Plitidepsin?

What is Plitidepsin?

Plitidepsin was originally obtained from a kind of protozoans, called Aplidiumalbicans. Plitidepsin, also known as dehydrodidemnin B, is a member of the class of compounds known as didemnins. Didemnins are […]

12 New Drugs Are Expected to be Approved for Marketing in Q4 2020

12 New Drugs Are Expected to be Approved for Marketing in Q4 2020

A recent article published by the well-known medical and health information website Xconomy pointed out that many new drugs are expected to be approved to enter the market before the end of […]

Application of benzimidazole in drugs

Application of benzimidazole in drugs

Benzimidazolium is a benzo heterocycle compound containing two nitrogen atoms. Benzimidazole has a special chemical structure which can form hydrogen bonds with enzymes and receptors in organisms, coordinate with metal […]

Effect of Phosphate Group Druggability of Compounds

Effect of Phosphate Group Druggability of Compounds

Phosphate is an important part of nucleic acid, a large number of which exists in the human body, it is a kind of harmless endogenous substances, which can help drugs […]

FDA approved 3-4 heterocyclic oxygen drugs

FDA approved 3-4 heterocyclic oxygen drugs

Oxygen heterocyclic ring is one of the most common heterocyclic rings in drugs and natural products. By the end of 2017, 311 drug molecules had at least one oxygen heterocyclic […]