Introduction of EGFR EGFR is the expression product of proto-oncogene C-ERBB1, the receptor of EGF cell proliferation and signal transduction. It is a member of epidermal growth factor receptor (HER) […]
Introduction of JAK-STAT signaling Pathway The JAK-STAT signaling pathway is a signal transduction pathway stimulated by cytokines, which is involved in many important biological processes such as cell proliferation, differentiation, […]
Oxygen heterocyclic ring is one of the most common heterocyclic rings in drugs and natural products. By the end of 2017, 311 drug molecules had at least one oxygen heterocyclic […]
Introduction P53 tumor suppressor gene is a kind of gene that inhibits cells from transforming into cancer cells in living organisms. There are oncogene and tumor suppressor gene in the […]
PI3K is called Phosphatidylinositol 3-kinase (phosphatidylinositol 3-kinase), which is involved in the regulation of various cellular functions such as cell proliferation, differentiation, apoptosis and glucose transport. An increase in PI3K […]
This article takes stock of the latest clinical development pipeline for lung and liver cancer. We calculated clinical trial data for clinical phase Ⅰ, and phase Ⅱ and phase Ⅲ […]
Cancer treatment has entered the era of precision medicine, and an important feature of precision medicine is the selection of targeted drugs based on the patient’s tumor characteristics. In the […]
Announcement of the 2018 Nobel Prize in Physiology or Medicine by Professor Thomas Perlmann, Secretary of the Nobel Committee for Physiology or Medicine, on 1 October 2018. It was awarded jointly […]
Introduction Oxygen is life sustaining, but its metabolism by organisms is not without consequences. Aerobic metabolism provides energy predominantly through mitochondrial oxidative phosphorylation. This process leads to the formation of by-products known […]
The D Vitamins and Their Precursors It must be recognized that there is not a single vitamin D compound but that there is a family of compounds that exhibit vitamin D […]
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