Anti-tumor

Cancer

Summary of Kinase Inhibitors | CDK2 and Its Inhibitors

CDKs belong to the serine/threonine protein kinase family, and their kinase activity requires binding to cyclins. Abnormalities in CDKs have been reported to cause proliferation, genomic and chromosomal instability that […]

IDO1 inhibitors

Recently Disclosed IDO1 Inhibitors

Abnormally high expression of indoleamine 2, 3-dioxygenase 1 (IDO1) is closely related to tumor immune escape and is an important target of tumor immunotherapy. In-depth research on the structure and […]

What is Exatecan Mesylate?

What is Exatecan Mesylate?

Exatecan Mesylate is a semi-synthetic water-soluble derivative of camptothecin. It is a new type of topoisomerase I inhibitor with anti-tumor activity. The anhydrous, alkali-free form of the drug is called […]