BOC Sciences Blog

Clinical Prospects of Aptamer Applications

Clinical Prospects of Aptamer Applications

Aptamers are short RNA/DNA oligonucleotide molecules that bind specifically to complementary target molecules. As potential recognition elements, aptamers show promising applications in both diagnosis and treatment. They offer diverse therapeutic and diagnostic […]

CD137/4-1BB combination therapy

Two Paths of Second-Generation 4-1BB Agonists

CD137/4-1BB combination therapy

Hypoglycemic Functional Factors in Natural Products and Their Mechanisms of Action

Hypoglycemic Functional Factors in Natural Products and Their Mechanisms of Action

Diabetes is a common clinical disease, and with the improvement of living standards, an increase in the number of obese people, and the intensification of aging populations, the incidence of […]

Mechanism of Action of Paclitaxel

Mechanism of Action of Paclitaxel

Paclitaxel is a natural anticancer drug with the molecular formula C47H51NO14. It has been widely used in the clinical treatment of breast cancer, ovarian cancer, and certain head and neck cancers, […]

Covalent, Non-covalent, and Covalent Reversible Drug Design in Medicinal Chemistry

Covalent, Non-covalent, and Covalent Reversible Drug Design in Medicinal Chemistry

Chemical drugs can be classified into three categories based on their binding modes: covalent drugs, non-covalent drugs, and covalent reversible drugs. Covalent drugs have strong binding ability and high efficacy, […]

Research progress on adjuvants for influenza vaccines

Research Progress on Adjuvants for Influenza Vaccines

Influenza is an acute and highly contagious respiratory disease caused by influenza A and B viruses. Annual influenza epidemics are caused by several different seasonal influenza viruses (i.e., A/H1N1, A/H3N2, B/Yamagata, […]

Types of Delivery Systems of mRNA Cancer Vaccines

Types of Delivery Systems of mRNA Cancer Vaccines

Brief Description of mRNA Delivery Systems As a therapeutic use, mRNA cancer vaccines have the advantages of high safety, strong immune activation ability, and short production cycle. Moreover, mRNA cancer […]

Review of Popular Targets

Review of Popular Targets

In recent years, antibody therapies (including traditional antibodies and nano-antibodies) have become an important means of treating a wide range of human malignant diseases, and more than 100 antibody therapies […]

Design Ideas for FDA-Approved Small Molecule Drugs in the third quarter of 2023

Design Ideas for FDA-Approved Small Molecule Drugs in the third quarter of 2023

FDA approved the marketing of 14 drugs in the third quarter of 2023, including 6 small molecule drugs. This article mainly focuses on the drug design ideas of small molecule drugs, hoping […]

Research progress on aluminum adjuvants and their mechanisms of action

Research progress on aluminum adjuvants and their mechanisms of action

What is Adjuvants? Adjuvants, also known as immunomodulators or immune enhancers, are an additive to vaccines. Adjuvants are non-specific immune enhancers that enhance or alter the type of immune response […]