BOC Sciences Blog

Immune checkpoint inhibitors: a new frontier in bladder cancer

Immune checkpoint inhibitors: a new frontier in bladder cancer

  Immunotherapy and immune checkpoint inhibition in particular present an exciting opportunity for the treatment of bladder cancer. Over the last 30 years, bladder cancer patients have seen few advances in the […]

Checkpoint inhibitors in immunotherapy of ovarian cancer

Checkpoint inhibitors in immunotherapy of ovarian cancer

Ovarian cancer is a cancerous growth arising from numerous parts, mainly the outer lining of the ovary called germinal epithelium. It is the fifth leading cause of cancer-related death among women, which causes […]

Immune checkpoint inhibitors: a patent review(2010-2015)

Immune checkpoint inhibitors: a patent review(2010-2015)

The ability of the immune system to detect and eliminate cancer was first proposed over 100 years ago. Since then, T cells reactive against tumor-associated antigens have been detected in […]

New Drugs for the Treatment of Myelofibrosis

New Drugs for the Treatment of Myelofibrosis

Myelofibrosis (MF) includes primary MF and MF that has arisen from an antecedent polycythemia vera (PV) or essential thrombocythemia (ET) (post-PV/ET MF). MF can affect patients in various ways, including progressive splenomegaly, cytopenias (particularly […]

Prevalence of legal and illegal stimulating agents in sports

Prevalence of legal and illegal stimulating agents in sports

The drive to compete and win is as old as humankind. Throughout history, athletes have sought foods and potions to enhance physical performance. Stimulants were one of the first groups of substances which […]

Efficacy of Bimatoprost in Glaucoma and Ocular Hypertension Unresponsive to Latanoprost

Efficacy of Bimatoprost in Glaucoma and Ocular Hypertension Unresponsive to Latanoprost

As a member of the prostamide class of ocular hypotensives, bimatoprost (Lumigan®) lowers intraocular pressure (IOP) by a dual mechanism: by increasing both pressure-dependent (presumed trabecular meshwork) and pressure-independent (presumed […]

Inhibition of prostatic cancer growth by ginsenoside Rh2

Inhibition of prostatic cancer growth by ginsenoside Rh2

Prostate cancer develops in the prostate, which is a gland in the male reproductive system. Prostate cancers generally grow slowly. However, aggressive prostate cancers do occur, which are capable of […]

Anticholinergic Treatment in Airways Diseases

Anticholinergic Treatment in Airways Diseases

Acute and chronic airways diseases represent a large proportion of the inpatient and outpatient population continuously under the care of pulmonary physicians and primary healthcare providers. This review article aims […]

Pharmacokinetic properties and metabolism of idebenone

Pharmacokinetic properties and metabolism of idebenone

Idebenone (2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone) is a synthetic analogue of ubiquinone, an essential constituent of the electron transport chain and a vital cell membrane anti-oxidant. It has been shown that patients with Friedreich […]

Photoprotective effects of nicotinamide

Photoprotective effects of nicotinamide

In Australia, the lifetime risk of developing non-melanoma skin cancer such as basal cell carcinoma (BCC) or squamous cell carcinoma (SCC) is almost 70% for men and 60% for women. […]