The concept of anaplerosis The oxidation of acetyl groups in the citric acid cycle (CAC) involves eight reactions, which (i) convert the two carbons of acetyl to CO2, and (ii) regenerate the […]
The objective of this study was to determine the potential role of the cardiotonic steroid marinobufagenin in the mechanisms of nociceptive signal modulation. It is known that the first phase of the […]
Se is incorporated into antioxidant selenoproteins, making it an essential micronutrient for animals, microorganisms and some other eukaryotes. In addition to the basic nutritional requirements for Se, it has become increasingly evident that […]
Organic foodstuffs are defined to be produced under controlled cultivation conditions according to the provisions of the regulation on organic farming of the European community. Grain based foodstuffs of organical […]
Eradication of hepatitis C virus (HCV) infection is extremely important to either cure hepatitis or prevent the progression of hepatic fibrosis and the development of hepatocellular carcinoma. Antiviral therapy using peginterferon and […]
Free radicals induce oxidative damage in vivo causing aging and various diseases. They are also the major cause for deterioration, quality loss, and shelf life reduction in oils/fats and fat-containing systems. There are […]
Renal cell cancer (RCC) is responsible for 3.7 % of all cancers diagnosed yearly and is ranked as the third most common urological cancer in the US population. The average age at diagnosis […]
Non-small cell lung cancer (NSCLC) is a leading cause of death among cancer patients. The 5-year overall survival rate in patients with localized cancer is 55.2 %, and this decreases to 4.3 % […]
Heat shock protein 90 (Hsp90) is a highly conserved molecular chaperone which modulates cellular homeostasis and environmental stress responses by interacting with more than 200 proteins, also known as Hsp90 client proteins, […]
Cancer is primarily a disease of the older adult with more than 50 % of new cases occurring in adults older than 65 years. The care of older adults with cancer can […]