What is Biotin? Biotin, with a molecular weight of 244.31, consists of two cyclic structures. The first ring is the imidazolone ring, the primary site for binding with avidin; the […]
In order to more effectively deliver chemotherapy drugs, Small Molecule Drug Conjugates (SMDC), Antibody Drug Conjugates (ADC), and Degradation Antibody Conjugates (DAC) have been successively explored and developed, enhancing the […]
There are various techniques for the preparation of microspheres, and the selection of an appropriate method depends on the physicochemical properties of the drug. Currently, the most widely used methods […]
The popularity of thiol coupling in ADC preparation can be attributed to three factors: It is essential to note that a reduction step is always required before coupling to release […]
Peptide Nucleic Acid (PNA) is a synthetic polymer similar to DNA or RNA. PNA can be said to have been born in Denmark, where it was originally developed by Peter E. […]
With the rapid development of biotechnology and molecular medicine, the introduction of mRNA as a vaccine or therapeutic agent enables the production of almost any desired functional protein/peptide within the […]
Aptamers are short RNA/DNA oligonucleotide molecules that bind specifically to complementary target molecules. As potential recognition elements, aptamers show promising applications in both diagnosis and treatment. They offer diverse therapeutic and diagnostic […]
CD137/4-1BB combination therapy
Diabetes is a common clinical disease, and with the improvement of living standards, an increase in the number of obese people, and the intensification of aging populations, the incidence of […]
Paclitaxel is a natural anticancer drug with the molecular formula C47H51NO14. It has been widely used in the clinical treatment of breast cancer, ovarian cancer, and certain head and neck cancers, […]