BOC Sciences Blog

Nat Commun: New method may help study pathogenesis of Parkinson’s disease

Nat Commun: New method may help study pathogenesis of Parkinson’s disease

NMDARs (N-methyl-D-aspartate receptors) can act as valves for nerve cells and control the flow of electrical signals in the brain. This particular class of receptors is suspected of being present […]

Lilly’s RET inhibitor LOXO-292 receives FDA priority review

Lilly’s RET inhibitor LOXO-292 receives FDA priority review

Lilly recently announced that its RET inhibitor, selpercatinib (loxo-292), has been granted priority review status by the U.S. FDA and is expected to accelerate its approval for the treatment of […]

Nat Commun: SKP2 inhibitors such as niclosamide reduce MERS-CoV coronavirus replication in vitro by up to 28,000 times

Nat Commun: SKP2 inhibitors such as niclosamide reduce MERS-CoV coronavirus replication in vitro by up to 28,000 times

The Middle East Respiratory Syndrome (MERS) Coronavirus (MERS-CoV) was first discovered in 2012 and can cause severe or even fatal pneumonia. There is currently no effective treatment for MERS-CoV. In […]

p53 target new drug! Aprea’s Blood Cancer Combination Therapy Receives FDA Breakthrough Therapy Designation

p53 target new drug! Aprea’s Blood Cancer Combination Therapy Receives FDA Breakthrough Therapy Designation

Aprea Therapeutics is a Boston-based biopharmaceutical company focused on developing and commercializing innovative cancer therapies that reactivate the tumor suppressor protein p53. Recently, the company announced that the U.S. food […]

When will we find an effective drug for the 2019 novel coronavirus?

When will we find an effective drug for the 2019 novel coronavirus?

Related Products: Remdesivir 2019-nCoV was discovered because of a viral pneumonia case in Wuhan, China in 2019. At present, the 2019-nCoV has shown a very strong ability of human-to-human transmission and […]

The Things You Need to Know about 2019-nCov

The Things You Need to Know about 2019-nCov

Since December 2019, the newly discovered coronavirus (2019-nCov) has caused an outbreak of pneumonia in Wuhan, China, and caused great public concern. At present, the Chinese government has implemented a […]

Dose and Safety of Remdesivir

Dose and Safety of Remdesivir

Related Products: Remdesivir It is reported that Remdesivir has begun a phase III clinical study against new coronavirus (2019-nCoV) at China-Japan Friendship Hospital. Gilead has done a lot of research on […]

Can Remdesivir outwit the 2019 novel coronavirus ?

Can Remdesivir outwit the 2019 novel coronavirus ?

Related Products: Remdesivir In response to the outbreak of pneumonia caused by the new coronavirus, scientific research institutions and pharmaceutical companies around the world are stepping up vaccine research and development […]

Tau protein identified as a key driver of Alzheimer’s disease

Tau protein identified as a key driver of Alzheimer’s disease

In a study published in Science Translational Medicine, a new study by scientists at the center for memory and aging at the University of California, San Francisco (UCSF), shows that […]

New target for Alzheimer’s disease-MSUT2

New target for Alzheimer’s disease-MSUT2

After A string of disappointing clinical trials targeting the amyloid β-protein(Aβ), researchers in the field of Alzheimer’s disease (AD) are paying more attention to the tau protein, another culprit in the disease. Like Aβ, […]