BOC Sciences Blog

Nat Med: disaster comes from the nose! SARS-CoV-2 can invade the body through key nasal cells!

Nat Med: disaster comes from the nose! SARS-CoV-2 can invade the body through key nasal cells!

Two special cell types in the nose have been identified as possible initial infection sites of COVID-19 coronavirus. Scientists have found that goblet cells and ciliated cells in the nose […]

Carbomer

Carbomer

What is carbomer? Carbomer is a kind of polymer formed by chemical cross-linking of acrylic acid or acrylate with allyl ether, including polyacrylic acid (homopolymer) and long-chain alkyl alcohol acrylate polymer […]

Will small molecular drugs be the “savior” of SARS-CoV-2?

Will small molecular drugs be the “savior” of SARS-CoV-2?

A novel coronavirus called SARS-CoV-2 (previously known as 2019-nCoV) is spreading widely and rapidly around the world. The disease of SARS-CoV-2 infection is termed Coronavirus Disease 2019 (COVID-19) by WHO. […]

Heavy news for diabetes! Johnson & Johnson Invokana approved for use in patients with type 2 diabetes and diabetic nephropathy

Heavy news for diabetes! Johnson & Johnson Invokana approved for use in patients with type 2 diabetes and diabetic nephropathy

Johnson & Johnson (JNJ) ‘s Janssen Pharmaceuticals has announced that Health Canada has approved a new indication for the glucose-lowering drug Invokana (canagliflozin): Complementary drugs for standard care therapies for […]

Nat Commun: New method may help study pathogenesis of Parkinson’s disease

Nat Commun: New method may help study pathogenesis of Parkinson’s disease

NMDARs (N-methyl-D-aspartate receptors) can act as valves for nerve cells and control the flow of electrical signals in the brain. This particular class of receptors is suspected of being present […]

Lilly’s RET inhibitor LOXO-292 receives FDA priority review

Lilly’s RET inhibitor LOXO-292 receives FDA priority review

Lilly recently announced that its RET inhibitor, selpercatinib (loxo-292), has been granted priority review status by the U.S. FDA and is expected to accelerate its approval for the treatment of […]

Nat Commun: SKP2 inhibitors such as niclosamide reduce MERS-CoV coronavirus replication in vitro by up to 28,000 times

Nat Commun: SKP2 inhibitors such as niclosamide reduce MERS-CoV coronavirus replication in vitro by up to 28,000 times

The Middle East Respiratory Syndrome (MERS) Coronavirus (MERS-CoV) was first discovered in 2012 and can cause severe or even fatal pneumonia. There is currently no effective treatment for MERS-CoV. In […]

p53 target new drug! Aprea’s Blood Cancer Combination Therapy Receives FDA Breakthrough Therapy Designation

p53 target new drug! Aprea’s Blood Cancer Combination Therapy Receives FDA Breakthrough Therapy Designation

Aprea Therapeutics is a Boston-based biopharmaceutical company focused on developing and commercializing innovative cancer therapies that reactivate the tumor suppressor protein p53. Recently, the company announced that the U.S. food […]

When will we find an effective drug for the 2019 novel coronavirus?

When will we find an effective drug for the 2019 novel coronavirus?

Related Products: Remdesivir 2019-nCoV was discovered because of a viral pneumonia case in Wuhan, China in 2019. At present, the 2019-nCoV has shown a very strong ability of human-to-human transmission and […]

The Things You Need to Know about 2019-nCov

The Things You Need to Know about 2019-nCov

Since December 2019, the newly discovered coronavirus (2019-nCov) has caused an outbreak of pneumonia in Wuhan, China, and caused great public concern. At present, the Chinese government has implemented a […]