BOC Sciences Blog

SDS-PAGE: Separation of Proteins Based on Size

What is SDS-PAGE electrophoresis? SDS-PAGE electrophoresis, short for sodium dodecyl sulfate polyacrylamide gel electrophoresis, is a kind of commonly used protein extraction technology to polyacrylamide gel is made up of […]

EDTA used in experimental research and molecular biology

Application of EDTA in experimental research and molecular biology

Ethylene Diamine Tetraacetic Acid (EDTA) is an important complex agent. EDTA has a wide range of uses, can be used as a bleaching fixing solution for color sensitive materials washing […]

nanocrystalline

Development and application of nanocrystalline technology in the field of new drugs

For a long time, the poor solubility and low bioavailability of APIhave been a major problem for drug developers, and the low solubility has led to the limitation of its […]

PCR additives

Enhancement of DNA amplification efficiency by using PCR additives

PCR additives play a crucial role in the PCR process, acting on various stages of the PCR reaction through different mechanisms, affecting amplification efficiency, specificity, and yield. The mechanisms of […]

Exploration and innovation of Linker features in PROTAC design

Exploration and innovation of Linker features in PROTAC design

Targeted Chimera Proteolysis (PROTAC) technology represents a breakthrough development in the field of drug discovery, utilizing the ubiquitin proteasome system to specifically degrade disease-associated proteins. PROTACs has a two-part function structure, that […]

Current status and future opportunities of vaccine adjuvants

Current status and future opportunities in vaccine adjuvant research

Vaccines are one of the most important inventions in human history, which has revolutionized human life and health. Typically, vaccines work by triggering an innate immune response and stimulating antigen-presenting […]

New drug approved by the FDA in 2024

New drug approved by the FDA in the first half of 2024

In the first half of the year, the FDA approved a number of landmark drugs, and there are many highlights: Rezdiffra, the first non-alcoholic steatohepatitis drug in 40 years, was […]

Experience sharing-Immunodiagnostic buffer

Experience sharing-Immunodiagnostic buffer

In the development of immunoassay reagents, buffer is typically the second most critical factor after core materials. It can affect various fundamental properties of the reagents, such as stability, sensitivity, […]

What is HEPES Buffer Solution?

What is HEPES Buffer Solution?

The buffering capacity of HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid) buffer solution derives from its chemical structure and acid-base equilibrium properties. Specifically, its buffering capacity is due to the equilibrium reactions between the acidic […]

disaccharide

What is disaccharide?

A disaccharide is an elementary form of carbohydrate that is necessary for the intricate web of metabolic processes that keep life alive. These molecules constitute the combination of two monosaccharide […]