BOC Sciences Blog

FDA-Approved Nucleic Acid Drugs

With the continuous development of molecular biology technology, the relationship between gene mutations and diseases has gained more and more in-depth understanding. Nucleic acids have attracted much attention because of […]

Strategies to Enhance Oligonucleotide Drug Delivery

1. Chemistry Modification Chemical modification represents one of the most effective approaches to enhance oligonucleotide drug delivery. Modification of the nucleic acid backbone, the ribose sugar moiety and the nucleobase […]

The Sixteen Most Frequently Encountered Problems in Cell Culture

The Sixteen Most Frequently Encountered Problems in Cell Culture

Cell culture refers to a method that simulates the internal environment (sterile, suitable temperature, pH, and certain nutritional conditions, etc.) in vitro to make it survive, grow, reproduce and maintain […]

Prospects of PD-1/PDL-1 Inhibitors in Cancer Immunotherapy

Prospects of PD-1/PDL-1 Inhibitors in Cancer Immunotherapy

In recent years, immunotherapy aimed at reactivating weakened immune cells in cancer patients has achieved remarkable results, especially immune checkpoint inhibitors, such as programmed cell death protein-1 (PD-1) and cytotoxic […]

Nanomedicine and Nanomedicine Design

Nanomedicine and Nanomedicine Design

What is nanomedicine Nanomaterials refer to materials with a spatial size of 1-100 nm (see Figure 1). Nanomedicine refers to various types of nanomaterials that can play a role in […]

Application of Nucleotides in the Direction of RNA Vaccines

Application of Nucleotides in the Direction of RNA Vaccines

Introduction to RNA vaccines RNA vaccines are composed of the nucleic acid RNA, which encode antigen genes of an infectious agent. When administered to host cells, the RNA is translated […]

Application of Nucleotides in Kits

Application of Nucleotides in Kits

Nucleotides are compounds composed of purine bases or pyrimidine bases, ribose or deoxyribose, and phosphoric acid. They are also called nucleotides. Five-carbon sugars and organic bases synthesize nucleosides, and nucleosides […]

Application of Nucleotides in PCR

Application of Nucleotides in PCR

Discovery and development of PCR Polymerase chain reaction (PCR) is an in vitro diagnostic technique that can replicate or amplify target DNA billions of times in an hour or less. […]

Nucleotide in Nucleic Acid Medicine

Nucleotide in Nucleic Acid Medicine

Nucleic acid and nucleic acid drugs Nucleic acid is the carrier of life genetic information. It has both the storage function of life information and the active function of biocatalysis. […]

Probody Antibody Prodrug Technology

Probody Antibody Prodrug Technology

Background After more than 30 years of development, antibody drugs have become one of the most important branches in the field of biopharmaceuticals, with sales increasing year by year. The […]