Nucleotides are compounds composed of purine bases or pyrimidine bases, ribose or deoxyribose, and phosphoric acid. They are also called nucleotides. Five-carbon sugars and organic bases synthesize nucleosides, and nucleosides […]
Discovery and development of PCR Polymerase chain reaction (PCR) is an in vitro diagnostic technique that can replicate or amplify target DNA billions of times in an hour or less. […]
Nucleic acid and nucleic acid drugs Nucleic acid is the carrier of life genetic information. It has both the storage function of life information and the active function of biocatalysis. […]
Background After more than 30 years of development, antibody drugs have become one of the most important branches in the field of biopharmaceuticals, with sales increasing year by year. The […]
Plitidepsin was originally obtained from a kind of protozoans, called Aplidiumalbicans. Plitidepsin, also known as dehydrodidemnin B, is a member of the class of compounds known as didemnins. Didemnins are […]
Pam3CSK4 is a synthetic triacylated lipopeptide (LP) which is similar to bacterial LPs that have an acylated amino terminus. Bacterial LPs are found in both Gram-positive and Gram-negative bacteria, and […]
Glutathione (γ-glutatamylcysteinylglycine, GSH) is a tripeptide containing a γ-amide bond and a sulfhydryl group, consisting of glutamate, cysteine and glycine, and is present in almost every cell of the body. […]
Hydroxypropyl-β-cyclodextrin can be abbreviated as HPCD. it is in the form of a white powder and has good solubility in water and can be dissolved in 50% ethanol and methanol. […]
The molecular weight of peptide drugs is between small molecule drugs (<500 Da) and biological products (>5000 Da). The FDA defines peptides as polymers composed of less than 40 amino […]
In the latest issue of the JMC journal, a review article, entitled “A Decade of FDA-Approved Drugs (2010-2019): Trends and Future Directions”, was published, which analyzed and summarized the FDA-approved […]