Why oligonucleotide drugs? Synthetic oligonucleotides are the key factor in almost all molecular biological methodologies. They are used in PCR, reverse transcription, sequencing, gene editing, synthetic biology, cloning, single nucleotide […]
1. Respiratory system 1.1. Lung cancer Drug Name Trade name CAS Target Description Approved Status Gefitinib lressa 184475-35-2 EGFR Gefitinib effectively inhibits all tyrosine phosphorylation sites on EGFR in both […]
Flavors and fragrances are pivotal in the food industry, enhancing the sensory attributes of food products and significantly influencing consumer preferences. Fragrances are added in small amounts in the food […]
In 2007, Japanese professors firstly discovered ALK rearrangement and identified the fusion of ALK and EML4 in non-small cell lung cancer specimens. EML4 can promote the activation of ALK kinase […]
In 2001, the FDA approved Imatinib, the first drug to be developed by targeting a specific protein kinase and the first molecularly targeted drug to fight cancer. It was considered […]
Since the outbreak of COVID-19, the industry has reached a peak as terms such as “national nucleic acid test” has become increasingly popular and molecular diagnosis has been widely known […]
Pharmaceutical analysis and testing can study the composition, physical and chemical properties, authenticity, purity, and the content of active ingredients of drugs, which ensures that people can use drugs reasonably […]
CDKs belong to the serine/threonine protein kinase family, and their kinase activity requires binding to cyclins. Abnormalities in CDKs have been reported to cause proliferation, genomic and chromosomal instability that […]
MYC protein is an inherently disordered protein, which lacks a hydrophobic pocket or groove suitable for binding small molecule compounds. Currently, no small molecule compounds that can bind MYC have […]
Facing the Coronavirus with continuous mutations, researchers are working hard to develop effective and broad-spectrum anti-Coronavirus drugs and vaccines. At the end of 2021, the small molecule oral drug was […]