The launch of two mRNA vaccines in 2020 marked the formal entry of mRNA technology into the commercial era. Strong vaccine demand is expected to bring bright prospects to the entire […]
Metabolic syndrome refers to a class of complex metabolic disorders, including adipose tissue accumulation, insulin resistance, diabetes, hyperinsulinemia, hypertension, and dyslipidemia, characterized by high levels of triglycerides (TG) and high-density […]
Globally, the COVID-19 pandemic has significantly accelerated the development of mRNA technology platforms and mRNA industry chains. The first mRNA drug (BNT162b2 vaccine) was granted emergency use authorization by the […]
What are the methods of heating in an organic chemical reaction? Organic reactions are most commonly heated through the asbestos mesh and cannot be heated directly by fire. Otherwise, the instrument […]
Genotoxic impurities can directly act on DNA in the human body, causing DNA damage and having carcinogenic, teratogenic, or mutagenic properties. A small amount of genotoxic impurities can also cause great […]
The analysis of impurities in drugs is a very important part. This blog focuses on the important role of the source analysis of impurities and the development of analytical techniques in the […]
Overview of Suzuki coupling reaction In the entire Suzuki-coupling reaction cycle, the oxidation-addition reaction of Pd(0) with halogenated aromatics to produce the Pd(II) complex is considered to be the decisive […]
In recent years, antibody-drug conjugates (ADCs) have achieved substantial success in cancer therapy. Typically, an antibody or peptide in a conjugated drug acts as a precisely located “navigator” while a small-molecule […]
Summary Heterocyclic compounds with aromatic characteristics are called aromatic heterocyclic compounds, which can be classified into monoaromatic heterocycles and fused heterocycles. The common monoaromatic heterocycles are five-membered Furan, Pyrrole, Thiophene, Pyrazole, Imidazole, […]
Innovative drug research and development is a very complicated and risky process from discovery to marketing, which includes preclinical research, clinical trial application, clinical trial (also divided into clinical phases […]