Pfizer’s mRNA vaccine for COVID has reignited the passion for using ribonucleic acid (RNA) as a therapeutic target. However, targeting RNA with small molecules is extremely challenging. RNA only has […]
The core technologies of oligonucleotide drug development include sequence design, synthesis and modification, isolation and purification, and delivery techniques. The production of oligonucleotide raw materials adopts solid-phase synthesis technology, with […]
Mechanisms of Immune Escape in Tumors Although the human immune system uses powerful immune cells and various immune measures, some immunogenic tumors evade clearance after initially being attacked by the […]
Purines are heterocyclic compounds composed of a pyrimidine ring and an imidazole ring and are the main components of nucleic acids. Their derivatives, such as adenine, guanine, and xanthine, are […]
Nucleic acid is a biopolymer compound composed of nucleotides and is one of life’s basic substances. It is widely found in all animal and plant cells, microorganisms, and organisms, and […]
The launch of two mRNA vaccines in 2020 marked the formal entry of mRNA technology into the commercial era. Strong vaccine demand is expected to bring bright prospects to the entire […]
Metabolic syndrome refers to a class of complex metabolic disorders, including adipose tissue accumulation, insulin resistance, diabetes, hyperinsulinemia, hypertension, and dyslipidemia, characterized by high levels of triglycerides (TG) and high-density […]
Globally, the COVID-19 pandemic has significantly accelerated the development of mRNA technology platforms and mRNA industry chains. The first mRNA drug (BNT162b2 vaccine) was granted emergency use authorization by the […]
What are the methods of heating in an organic chemical reaction? Organic reactions are most commonly heated through the asbestos mesh and cannot be heated directly by fire. Otherwise, the instrument […]
Genotoxic impurities can directly act on DNA in the human body, causing DNA damage and having carcinogenic, teratogenic, or mutagenic properties. A small amount of genotoxic impurities can also cause great […]