Oligonucleotides are short synthetic DNA or RNA polymers, which modulate gene expression through Watson-Crick base pairing with targeted nucleic acids. Oligonucleotides regulate gene expression through a series of processes, including […]
Drug Modification Drug modification involves altering the chemical structure of the drug itself (such as functional groups, amino acids or nucleic acid skeletons) and coupling the drug with known partial […]
Introduction of IAP Apoptosis, or programmed death, is a natural cell cycle process designed to eliminate unwanted or damaged cells from the body. In healthy tissues, there is a good […]
Kinases have become an extremely important molecular target for a range of therapeutic targets. The kinase inhibitors are a large group of unique and potent antineoplastic agents which specifically target […]
Proteasome is the main pathway by which misfolded proteins and other proteins are proteolyzed during protein synthesis. It is found in all eukaryotic cells, archaea and some bacteria and is […]
Antibiotics have highly effective bacteriostatic effects and are widely used in the prevention and treatment of human and animal diseases. The antibacterial mechanism of antibiotics mainly includes hindering the synthesis […]
Background of Dopamine and Its Receptors In 1957, the Swedish scientist Arvid Carlsson first discovered dopamine and proposed that dopamine is not only a precursor of norepinephrine, it is also […]
Compared with biological drugs, small molecule drugs have greater advantages in R&D cost and process maturity, and they are still the main battlefield for drug research and development. According to […]
With the continuous development of molecular biology technology, the relationship between gene mutations and diseases has gained more and more in-depth understanding. Nucleic acids have attracted much attention because of […]
Cell culture refers to a method that simulates the internal environment (sterile, suitable temperature, pH, and certain nutritional conditions, etc.) in vitro to make it survive, grow, reproduce and maintain […]