Research Hotspot

ADCs Make Their Mark in HER-Positive Cancers

ADCs Make Their Mark in HER-Positive Cancers

Members of the human epidermal growth factor receptor (HER) family, including HER1 (EGFR), HER2, HER3, and HER4, play central roles in regulating cell proliferation, survival, differentiation, and migration. Overexpression of […]

Therapeutic Opportunities and Challenges for Lipogenesis Inhibitor Development

Therapeutic Opportunities and Challenges for Lipogenesis Inhibitor Development

Fatty acids are essential for cell survival and function as biological energy substrates, structural components, and signaling molecules. Given their critical role, cells have evolved mechanisms to produce fatty acids from […]

10 Small Molecule Drugs Approved for COVID-19

A Glance at 10 Small Molecule Drugs Approved for COVID-19

COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 is a betacoronavirus and possesses a positive-sense single-stranded RNA genome that contains 14 open reading frames (ORFs). Two […]

Cancer

Immune Checkpoint Target: TIGIT

TIGIT is considered to be one of the most promising and potential targets, and a variety of evidence supports that TIGIT plays a key role in limiting the adaptive and […]

Fluorescent Labels

Introduction to Fluorescent Labels: Cyanine Dyes Cy7, Cy5, Cy5.5, and Cy3

BOC Sciences provides varieties of fluorescent-labeled products and services to assist research in related fields.

SARS

Mesothelin: A New Target for Cancer Therapy

Structure and function of mesothelin The MSLN gene is located in chromosome 16p13. It contains 17 exons, with a cDNA length of about 2138bp, has a 1884-bp open reading frame, […]

The Research Progress in SHP2 and the Inhibitors

BOC Sciences has directed sincere efforts toward the R&D of small-molecule inhibitors (inhibitors, agonists, and modulators), which greatly free researchers from material outsourcing and selection workload.

mRNA-vaccine

Common Nucleosides as Raw Materials for In Vitro Diagnosis

Messenger RNA (mRNA) was first discovered in the 1960s, but its instability and immunogenicity have severely hindered the development of mRNA therapy. To solve this problem, researchers have contrived several […]

FDA Approved ALK Inhibitors for ALK-Positive Non-Small Cell Lung Cancer

FDA Approved ALK Inhibitors for ALK-Positive Non-Small Cell Lung Cancer

Lung cancer is a major type of cancer in the world, with the highest morbidity and mortality among all malignant tumors. ALK-positive non-small cell lung cancer (ALK+ NSCLC) is a […]

Distearyl Phthalic Acid Amides to Accelerate Cosmetics Formulation and Manufacture

Distearyl Phthalic Acid Amides to Accelerate Cosmetics Formulation and Manufacture

Distearyl Phthalic Acid Amide, also known as N, N-Stearyl Phthalic Acid Amide or N, N-Tollow Phthalic Acid Amide, is a biodegradable ingredient contained in many cosmetics and personal care products, […]