Research Hotspot

Nat Commun: SKP2 inhibitors such as niclosamide reduce MERS-CoV coronavirus replication in vitro by up to 28,000 times

Nat Commun: SKP2 inhibitors such as niclosamide reduce MERS-CoV coronavirus replication in vitro by up to 28,000 times

The Middle East Respiratory Syndrome (MERS) Coronavirus (MERS-CoV) was first discovered in 2012 and can cause severe or even fatal pneumonia. There is currently no effective treatment for MERS-CoV. In […]

When will we find an effective drug for the 2019 novel coronavirus?

When will we find an effective drug for the 2019 novel coronavirus?

Related Products: Remdesivir 2019-nCoV was discovered because of a viral pneumonia case in Wuhan, China in 2019. At present, the 2019-nCoV has shown a very strong ability of human-to-human transmission and […]

Dose and Safety of Remdesivir

Dose and Safety of Remdesivir

Related Products: Remdesivir It is reported that Remdesivir has begun a phase III clinical study against new coronavirus (2019-nCoV) at China-Japan Friendship Hospital. Gilead has done a lot of research on […]

Can Remdesivir outwit the 2019 novel coronavirus ?

Can Remdesivir outwit the 2019 novel coronavirus ?

Related Products: Remdesivir In response to the outbreak of pneumonia caused by the new coronavirus, scientific research institutions and pharmaceutical companies around the world are stepping up vaccine research and development […]

Tau protein identified as a key driver of Alzheimer’s disease

Tau protein identified as a key driver of Alzheimer’s disease

In a study published in Science Translational Medicine, a new study by scientists at the center for memory and aging at the University of California, San Francisco (UCSF), shows that […]

Highlights of HIV research in December 2019

Highlights of HIV research in December 2019

Human immunodeficiency virus (HIV), or AIDS (Acquired Immunodeficiency Syndrome) virus, is a virus that causes defects in the human immune system. HIV destroys the body’s T lymphocytes, thereby blocking the […]

PROTAC technology: Small molecule drug research and development mass murderer is coming! (Ⅱ)

PROTAC technology: Small molecule drug research and development mass murderer is coming! (Ⅱ)

Protein degradation targeted chimera (PROTAC) PROTAC technology began in 2001 that uses the ubiquitin-proteasome system (UPS), the intracellular “cleaner” for cleaning up denatured, mutated, or harmful proteins in cells. PROTAC, which uses […]

PROTAC technology: Small molecule drug research and development mass murderer is coming! (Ⅰ)

PROTAC technology: Small molecule drug research and development mass murderer is coming! (Ⅰ)

Preface Judging from the global drug sales trend in recent years, biological drugs have begun to become popular, while sales of small molecular drugs are declining. Innovations in research and […]

Immuno-Oncology

Immuno-Oncology

The upsurge of research and development of Immuno-Oncology (IO) therapeutic drugs has been in full swing in recent years, which dominates the commanding point of public opinion in the field […]

Hot spots in the field of drugs in July

Hot spots in the field of drugs in July

  Nat Med: a special intestinal bacteria, which is expected to reduce the risk of cardiovascular disease by 50 percent of the population. In 2007, scientists at institutions such as […]