Inhibitor

Cancer

Summary of Kinase Inhibitors | CDK2 and Its Inhibitors

CDKs belong to the serine/threonine protein kinase family, and their kinase activity requires binding to cyclins. Abnormalities in CDKs have been reported to cause proliferation, genomic and chromosomal instability that […]

The Development of Small-molecule Inhibitors Targeting CD47

The Development of Small-molecule Inhibitors Targeting CD47

Abstract Immunotherapy has become an indispensable part of cancer treatment. A pivotal phagocytosis checkpoint, named cluster of differentiation 47 (CD47), which functions as a ‘don’t eat me’ signal to protect […]