On March 8, 2018, the U.S. Food and Drug Administration approved the expanded use of the anti-psychotic drug Latuda (also referred to as lurasidone HCI) for a new indication – to […]
Metformin has proven to be a “magic drug” beyond its application in treating diabetes. Over the past 20 years, metformin has become the mainstay of type 2 diabetes treatment and […]
Olaparib, also known as AZD-2281 or KU-59436, is a small molecule inhibitor of the nuclear enzyme poly (ADP-ribose) polymerase (PARP) with potential chemosensitizing, radiosensitizing, and antineoplastic activities. Olaparib selectively binds to […]
On Oct. 18, 2017, the Food and Drug Administration (FDA)’s Endocrinologic and Metabolic Drugs Advisory Committee (EMDAC) has unanimously voted 16-0 to support the approval of Novo Nordisk’s semaglutide, a […]
Maintenance of DNA topology is critical for normal DNA replication, transcription and repair in eukaryotic cells. One family of enzymes, the topoisomerases, is essential for this process. Eukaryotic topoisomerase I […]
The main control measures in cotton fields in China include chemical control, cultural control (e.g., intercropping with trap crops), physical control (e.g., light traps and sticky traps), and biological control […]
Acute myeloid leukemia (AML) is a rapidly progressing cancer that forms in the bone marrow and results in an increased number of white blood cells in the bloodstream. The National […]
On July 17, 2017, the U.S. Food and Drug Administration approved neratinib (Nerlynx, Puma Biotechnology, Inc.) for the extended adjuvant treatment of adult patients with early stage HER2-overexpressed/amplified breast cancer to […]
The concept of arming antibodies by conjugation to protein toxins dates back to 1970, and was followed a few years later by antibody conjugates with cytotoxic drugs. Antibody therapeutics have come of age […]
A systematic comparison of the ginsenosides and physicochemical properties of white ginseng (WG), red ginseng (RG) and black ginseng (BG) was performed. The purpose of the present study was to identify […]