Drug Discovery

The new method can significantly inhibit the metastasis of breast cancer.

The new method can significantly inhibit the metastasis of breast cancer.

Triple negative breast adenocarcinoma (triple negative breast cancer (TNBC) is a breast cancer with negative estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor-2 (HER-2). With unique […]

Which drug can reduce the risk of recurrence of contralateral breast cancer?

Which drug can reduce the risk of recurrence of contralateral breast cancer?

Breast cancer (BC) is a serious threat to women’s health of malignant tumors. According to the latest national cancer statistics released by the National Cancer Center, breast cancer is still […]

Latest Clinical Trials of AIDS and Hypertension

Latest Clinical Trials of AIDS and Hypertension

This article takes stock of the latest AIDS and hypertension research and development pipeline. We counted the data of phase Ⅰ, phase Ⅱ and phase Ⅲ clinical trials of AIDS […]

Me better drug-Pravastatin

Dyslipidemia is a common metabolic disease in modern people. Most of them are caused by many obstacles in the process of lipoprotein metabolism, lipoprotein metabolism disorder, and a large number […]

Progress in HIV Research in January 2019

Human immunodeficiency virus, HIV (AIDS, acquired immunodeficiency syndrome) virus is a virus that causes the deficiency of the human immune system. In 1983, HIV was first discovered in the United […]

EGFR-targeted Related Drugs

EGFR-targeted Related Drugs

Introduction of EGFR EGFR is the expression product of proto-oncogene C-ERBB1, the receptor of EGF cell proliferation and signal transduction. It is a member of epidermal growth factor receptor (HER) […]

Research and Development of Janus Kinase (JAK) Inhibitors

Introduction of JAK-STAT signaling Pathway The JAK-STAT signaling pathway is a signal transduction pathway stimulated by cytokines, which is involved in many important biological processes such as cell proliferation, differentiation, […]

FDA approved 3-4 heterocyclic oxygen drugs

FDA approved 3-4 heterocyclic oxygen drugs

Oxygen heterocyclic ring is one of the most common heterocyclic rings in drugs and natural products. By the end of 2017, 311 drug molecules had at least one oxygen heterocyclic […]

Star tumor suppressor gene p53

Introduction P53 tumor suppressor gene is a kind of gene that inhibits cells from transforming into cancer cells in living organisms. There are oncogene and tumor suppressor gene in the […]

Overview of PI3K inhibitors in research competition

PI3K is called Phosphatidylinositol 3-kinase (phosphatidylinositol 3-kinase), which is involved in the regulation of various cellular functions such as cell proliferation, differentiation, apoptosis and glucose transport. An increase in PI3K […]