Drug Discovery

Eight NMEs approved by FDA from January to June 2019

Eight NMEs approved by FDA from January to June 2019

The evaluation of drugs by FDA has always been the focus of pharmaceutical research all over the world, and the approval of NME (New molecular entity) to market is the […]

Pre-doxercalciferol

Pre-doxercalciferol is a precursor of doxercalciferol, a drug used for the treatment of secondary hyperparathyroidism and metabolic bone disease. Doxercalferol, the active ingredient of Hectorol®, is a synthetic vitamin D2 analog. […]

Eribulin

  Eribulin is an analog of halichondrin B, which is a macrocycle, a polyether, a polycyclic ether, a cyclic ketone, a primary amine compound, and a cyclic ketal. Eribulin is […]

Application of benzimidazole in drugs

Application of benzimidazole in drugs

Benzimidazolium is a benzo heterocycle compound containing two nitrogen atoms. Benzimidazole has a special chemical structure which can form hydrogen bonds with enzymes and receptors in organisms, coordinate with metal […]

Effect of Phosphate Group Druggability of Compounds

Effect of Phosphate Group Druggability of Compounds

Phosphate is an important part of nucleic acid, a large number of which exists in the human body, it is a kind of harmless endogenous substances, which can help drugs […]

The latest research report of Entrectinib

The latest research report of Entrectinib

ASCO 2019, the largest, highest academic and most authoritative clinical oncology conference in the world, was held in Chicago from May 31 to June 4. At the ASCO annual meeting, […]

Latest treatment for non-small cell lung cancer.

Latest treatment for non-small cell lung cancer.

The prognosis of patients with early lung cancer is better, but many patients with lung cancer are diagnosed with advanced stage, and the overall five-year survival rate is only about […]

Drugs from Natural Products

Drugs from Natural Products

With the development of scientific and technological means, there are many ways to obtain drugs, including separation from plants and other natural sources, synthetic chemistry, combinatorial chemistry and molecular modeling. […]

Latest Clinical Trials of Alzheimer’s disease and Liver Cancer

Latest Clinical Trials of Alzheimer’s disease and Liver Cancer

This paper takes an inventory of the latest clinical trials in the field of Alzheimer’s disease and liver cancer in the world as of May 6, 2019. The data source […]

Temsirolimus: a long-lived antineoplastic drug

Temsirolimus was developed by Hara Wyeth Pharmaceuticals and was approved for listing by FDA in May 2007 for the treatment of renal cell carcinoma. The drug is the first antineoplastic […]