Drug Discovery

Valinomycin is expected to treat sars-cov-2 infection

Valinomycin is expected to treat sars-cov-2 infection

Natural products are very important because they have significant medicinal properties such as antiviral, antimicrobial and anticancer activity. The latest breakthrough in DNA sequencing shows that many microbial genomes (such […]

Baicalin and baicalein can effectively inhibit SARS-CoV-2

Baicalin and baicalein can effectively inhibit SARS-CoV-2

Coronavirus type 2 of severe acute respiratory syndrome (SARS-cov-2) causes coronavirus disease (COVID-19) in humans and there is no cure. In the fight against COVID-19 epidemic, traditional Chinese medicine (TCM) […]

US clinical trials prove that remdesivir is effective in treating COVID-19!

US clinical trials prove that remdesivir is effective in treating COVID-19!

COVID-19 is still raging around the world. However, so far there is no clinical evidence that any drug is effective for COVID-19 patients. Remdesivir is one of many coronavirus treatment […]

Heavy news for diabetes! Johnson & Johnson Invokana approved for use in patients with type 2 diabetes and diabetic nephropathy

Heavy news for diabetes! Johnson & Johnson Invokana approved for use in patients with type 2 diabetes and diabetic nephropathy

Johnson & Johnson (JNJ) ‘s Janssen Pharmaceuticals has announced that Health Canada has approved a new indication for the glucose-lowering drug Invokana (canagliflozin): Complementary drugs for standard care therapies for […]

Lilly’s RET inhibitor LOXO-292 receives FDA priority review

Lilly’s RET inhibitor LOXO-292 receives FDA priority review

Lilly recently announced that its RET inhibitor, selpercatinib (loxo-292), has been granted priority review status by the U.S. FDA and is expected to accelerate its approval for the treatment of […]

p53 target new drug! Aprea’s Blood Cancer Combination Therapy Receives FDA Breakthrough Therapy Designation

p53 target new drug! Aprea’s Blood Cancer Combination Therapy Receives FDA Breakthrough Therapy Designation

Aprea Therapeutics is a Boston-based biopharmaceutical company focused on developing and commercializing innovative cancer therapies that reactivate the tumor suppressor protein p53. Recently, the company announced that the U.S. food […]

New target for Alzheimer’s disease-MSUT2

New target for Alzheimer’s disease-MSUT2

After A string of disappointing clinical trials targeting the amyloid β-protein(Aβ), researchers in the field of Alzheimer’s disease (AD) are paying more attention to the tau protein, another culprit in the disease. Like Aβ, […]

JAA: Oleander may be effective in treating HTLV-1 virus infection

JAA: Oleander may be effective in treating HTLV-1 virus infection

In a new study, researchers from Southern Methodist University and the University of Texas MD Anderson Cancer Center found that oleandrin can stop the spread of HTLV-1 by targeting a […]

What are the functions of Rapamycin? (II)

What are the functions of Rapamycin? (II)

PLoS Biol: Scientists reveal new mechanism of Rapamycin. doi: 10.1371 / journal.pbio.3000252 Recently, in a research report published in PLoS Biology, scientists from the University of Michigan revealed a new […]

What are the functions of Rapamycin? (I)

What are the functions of Rapamycin? (I)

Rapamycin (RAPA), also known as “sirolimus”, was first discovered by scientists in the soil of Easter Island, Chile in 1975 due to its strong antifungal properties. Rapamycin is a macrolide […]