Custom Synthesis

RNA Synthesis

Circular RNA Synthesis

The Background of Circular RNA Synthesis In recent years, nucleic acid therapy involving various types of ribonucleic acids (RNAs), including messenger RNA (mRNA), small interfering RNA (siRNA), and microRNA (miRNA), […]

Challenges of Oligonucleotide Drug Development

Challenges of Oligonucleotide Drug Development

The core technologies of oligonucleotide drug development include sequence design, synthesis and modification, isolation and purification, and delivery techniques. The production of oligonucleotide raw materials adopts solid-phase synthesis technology, with […]

powder

Overview of Purine, Nucleoside, and Sugar Molecule Building Blocks

Purines are heterocyclic compounds composed of a pyrimidine ring and an imidazole ring and are the main components of nucleic acids. Their derivatives, such as adenine, guanine, and xanthine, are […]

Nucleoside Monomers

Breaking the Barrier: Chemical Modification of Nucleoside Monomers

Small nucleic acid-based drugs, namely oligonucleotide drugs, are short-chain nucleic acids consisting of dozens of nucleotides in series. At present, most oligonucleotide drugs are obtained through solid-phase chemical synthesis by […]

Distearyl Phthalic Acid Amides to Accelerate Cosmetics Formulation and Manufacture

Distearyl Phthalic Acid Amides to Accelerate Cosmetics Formulation and Manufacture

Distearyl Phthalic Acid Amide, also known as N, N-Stearyl Phthalic Acid Amide or N, N-Tollow Phthalic Acid Amide, is a biodegradable ingredient contained in many cosmetics and personal care products, […]

Organofluorine in Medical Chemistry

The discovery of fluorine by Henri Moissan in 1886 is a landmark in the history of chemistry. In the past six decades, fluorine chemistry has developed from a curiosity to […]

Solid phase syntheses of S,N-substituted 2-mercaptobenzoimidazoles 

Solid phase syntheses of S,N-substituted 2-mercaptobenzoimidazoles 

  2-Mercaptobenzoimidazoles are an interesting class of heterocycles in medicinal chemistry as their core structure is part of different established therapeutics. The most prominent ones of these drugs are omeprazole, which acts as […]

Solid phase syntheses of S, N-substituted 2-mercaptobenzoimidazoles

Solid phase syntheses of S, N-substituted 2-mercaptobenzoimidazoles

2-Mercaptobenzoimidazoles are an interesting class of heterocycles in medicinal chemistry as their core structure is part of different established therapeutics. The most prominent ones of these drugs are omeprazole, which acts as a […]

Antitumor Drug Ingredient Etoposide Can be produced in Laboratory Now

Antitumor Drug Ingredient Etoposide Can be produced in Laboratory Now

Scientists have successfully found a way for producing an important cancer drug ingredient in lab recently, which may bring a decrease to the cost of the related drug as its […]

Supercomputers Assist In Modeling the Synthesis of Cellulose

Supercomputers Assist In Modeling the Synthesis of Cellulose

With the assistance of IBM supercomputers which is named as AVOCA, scientists can move a new step on the way to observe the basic structural substance-cellulose in plant cell walls, […]