BOC Sciences Blog

How to improve the developability of siRNA drugs?

How to improve the developability of siRNA drugs?

Research shows RNAi technology can now treat genetic diseases and cancer as well as various medical conditions through advanced biotechnology. Scientists use siRNA drugs as innovative treatments because they target specific […]

2024 Top 15 Surfactants Usage List

2024 Top 15 Surfactants Usage List

1. Cocamidopropyl Betaine Derived from coconut oil, it is mild, efficient, and multifunctional. Widely used in hair care products, it excels in cleansing and emulsifying, with additional cationic surfactant properties like […]

Approved Deuterated Drugs

Approved Deuterated Drugs

What are Deuterated Compounds? Deuterated compounds refer to new compounds obtained by replacing one or more C-H bonds in a molecule with D atoms. Deuterated reagents are an important class of […]

Common modifications and effects of oligonucleotide drugs

Common modifications and effects of oligonucleotide drugs

Oligonucleotides have shown efficient therapeutic effects in various fields, indicating their potential for disease treatment. However, due to poor in vivo stability, ineffective cellular uptake, and off-target effects including immune stimulation, […]

Ten Common Types of Bacterial Culture Media

10 Common Types of Bacterial Culture Media: Formulas, Preparation Methods and Characteristics

1.Nutrient Agar (NA) Formula: Beef extract: 3g Peptone: 5g Sodium chloride: 5g Agar: 15-20g Distilled water: 1000mL Preparation Method: Add all components to water and heat while stirring until completely […]

Current Status and Prospects of Oligonucleotide Drug Research and Development

Current Status and Prospects of Oligonucleotide Drug Research and Development

As a vital drug modality, the field of oligonucleotide development will continue to expand and strengthen in the coming years. Oligonucleotide therapeutics are a class of medicines composed of short […]

five popular RNA-LNP products lipid components

Lipid Components of 5 RNA-LNPs

The main challenge in RNA and other nucleic acid-based therapeutics is how to deliver genetic information to target cells in the body. This barrier is currently being addressed, partly due […]

Apoptosis vs Pyroptosis vs Necrosis vs Ferroptosis vs Autophagy

Apoptosis vs Pyroptosis vs Necrosis vs Ferroptosis vs Autophagy

Apoptosis Definition: Apoptosis refers to a highly organized, gene-controlled process in which cells actively undergo death. It plays a crucial role in maintaining tissue homeostasis and eliminating damaged, aging, or […]

Difference between the primary, secondary, tertiary and quaternary structures of nucleic acids

Difference between the primary, secondary, tertiary and quaternary structures of nucleic acids

Structure of nucleic acids is a big concept in biophysics. Nucleic acid structure is multi-level, multi-complex and unified: Primary, secondary, tertiary and quaternary structures constitute the full spatial conformation and […]

Applicaiton of Ribonuclease Targeting Chimeras (RIBOTACs)

Applicaiton of Ribonuclease Targeting Chimeras (RIBOTACs)

Ribonucleic acid (RNA) plays a critical role in cellular diversity and gene expression and may offer more drug targets than proteins. However, due to their small size and relatively poor […]