BOC Sciences Blog

Mechanism and application of cGAS-STING pathway

Mechanism and application of cGAS-STING pathway

cGAS/STING Innate Immune Signaling cGAS (cyclic GMP-AMP synthase) is a nucleotide transferase consisting of an unstructured, non-conserved N-terminal (130-150 residues) and a C-terminal containing an Mab21 domain and a highly […]

Protein Conjugation Methods

Protein Conjugation Methods

Protein-Protein Conjugation Methods Protein-protein conjugation is commonly used in immunoassays for enzyme-labeled antibodies or antigens, essentially preparing signal markers. The main protein-protein conjugation methods include the periodate oxidation method (direct […]

Emerging Drug Conjugates: A Comprehensive Overview

Emerging Drug Conjugates: A Comprehensive Overview

In recent years, with the continuous advancements in protein gene engineering and chemical conjugation technologies, the field of conjugated drugs has seen a blooming of diverse concepts, resulting in a […]

<strong>Chromatography for Protein Purification</strong>

Chromatography for Protein Purification

Chromatography is one of the most powerful techniques for protein purification. It allows for the separation of proteins based on their unique physicochemical properties. Here are the main types of […]

PEG for drug development

PEG for drug development

Wide applications of polyethylene glycol (PEG) Polyethylene glycol (PEG) is a polymer material that is usually soluble in water and many organic solvents, but insoluble in fatty hydrocarbons, benzene, ethylene glycol, etc. […]

What are the differences between PCR, qPCR, RT-PCR, and RT-qPCR?

What are the differences between PCR, qPCR, RT-PCR, and RT-qPCR?

What is Polymerase Chain Reaction (PCR)? PCR stands for Polymerase Chain Reaction which enables scientists to quickly amplify DNA inside laboratory environments. The process uses DNA polymerase’s catalytic ability to duplicate […]

<strong>Overview of Antifungal Drugs</strong>

Overview of Antifungal Drugs

Clinical fungal infections have become more frequent in recent years especially among patients with compromised immune systems like those suffering from HIV, cancer, or who have undergone organ transplants. Life-threatening […]

How to improve the developability of siRNA drugs?

How to improve the developability of siRNA drugs?

Research shows RNAi technology can now treat genetic diseases and cancer as well as various medical conditions through advanced biotechnology. Scientists use siRNA drugs as innovative treatments because they target specific […]

2024 Top 15 Surfactants Usage List

2024 Top 15 Surfactants Usage List

1. Cocamidopropyl Betaine Derived from coconut oil, it is mild, efficient, and multifunctional. Widely used in hair care products, it excels in cleansing and emulsifying, with additional cationic surfactant properties like […]

Approved Deuterated Drugs

Approved Deuterated Drugs

What are Deuterated Compounds? Deuterated compounds refer to new compounds obtained by replacing one or more C-H bonds in a molecule with D atoms. Deuterated reagents are an important class of […]